Ubwoko butandatu bwindwara zubuhumekero

Ibisobanuro bigufi:

Iki gikoresho gishobora gukoreshwa kugirango umenye neza aside nucleique ya SARS-CoV-2, virusi ya grippe A, virusi ya grippe B, adenovirus, mycoplasma pneumoniae na virusi yubuhumekero muri vitro.


Ibicuruzwa birambuye

Ibicuruzwa

Izina RY'IGICURUZWA

HWTS-OT058A / B / C / Z-Igihe nyacyo fluorescent RT-PCR ibikoresho byo kumenya ubwoko butandatu bwindwara zubuhumekero

Icyemezo

CE

Epidemiologiya

Indwara ya virusi ya Corona 2019, yitwa "COVID-19", yerekeza ku musonga watewe n'indwara ya SARS-CoV-2.SARS-CoV-2 ni coronavirus yo mu bwoko bwa β.COVID-19 ni indwara yandurira mu myanya y'ubuhumekero, kandi muri rusange abaturage bakunze kwibasirwa.Kugeza ubu, isoko y’ubwandu ni abarwayi banduye SARS-CoV-2, kandi abanduye ibimenyetso simusiga na bo bashobora kuba intandaro yo kwandura.Ukurikije iperereza ryakozwe muri iki gihe, igihe cyo gukora ni iminsi 1-14, cyane cyane iminsi 3-7.Umuriro, inkorora yumye n'umunaniro nibyo bigaragara.Abarwayi bake barwaye izuru, izuru ritemba, kubabara mu muhogo, myalgia na diyare.

Ibicurane, bizwi cyane ku izina rya "ibicurane", ni indwara ikabije y’ubuhumekero iterwa na virusi ya grippe.Yanduye cyane.Yandura cyane cyane gukorora no kwitsamura.Ubusanzwe itangira mu mpeshyi no mu itumba.Virusi y'ibicurane igabanyijemo ibicurane A, IFV A, ibicurane B, IFV B, na Grippe C, IFV C ubwoko butatu, byose ni virusi ifatanye, bitera indwara zabantu cyane cyane virusi ya grippe A na B, ni umurongo umwe, virusi ya RNA.Indwara y'ibicurane A ni indwara ikabije y'ubuhumekero, harimo H1N1, H3N2 ndetse n'ubundi bwoko butandukanye, bukunze kwibasirwa n'imihindagurikire y'ikirere."Shift" bivuga ihinduka rya virusi ya grippe A, bigatuma habaho virusi nshya "subtype".Virusi ya grippe B igabanijwemo imirongo ibiri, Yamagata na Victoria.Virusi y'ibicurane B ifite gusa antigenic drift, kandi irinda igenzura ry'umubiri w'umuntu no kurandurwa binyuze mu ihinduka ry’imiterere.Nyamara, umuvuduko w’ihindagurika rya virusi ya grippe B uratinda cyane ugereranije na virusi ya grippe A.Umugera wa grippe B urashobora kandi gutera indwara zubuhumekero zabantu kandi biganisha ku byorezo.

Adenovirus (AdV) ni iy'inyamabere adenovirus y’inyamabere, ikaba ari virusi ya ADN ikubye kabiri idafite ibahasha.Nibura genotypes 90 zabonetse, zishobora kugabanywa muri AG 7 subgenera.Indwara ya AdV irashobora gutera indwara zitandukanye, zirimo umusonga, bronhite, cystite, conjunctivitis y'amaso, indwara zo mu gifu na encephalite.Umusonga wa Adenovirus ni bumwe mu bwoko bukabije bw’umusonga wanduye mu bana, bangana na 4% -10% by'umusonga wanduye abaturage.

Mycoplasma pneumoniae (MP) ni ubwoko bwa mikorobe ntoya ya prokaryotic, iri hagati ya bagiteri na virusi, ifite imiterere y'utugari ariko nta rukuta rw'akagari.Depite ahanini itera indwara zubuhumekero zabantu, cyane cyane kubana ndetse nabasore.Irashobora gutera mycoplasma pneumonia yumuntu, kwandura kwubuhumekero bwabana hamwe numusonga udasanzwe.Kugaragara kwa clinique biratandukanye, ibyinshi muri byo ni inkorora ikabije, umuriro, gukonja, kubabara umutwe, kubabara mu muhogo.Indwara y'ubuhumekero yo hejuru hamwe n'umusonga wa bronchial niwo ukunze kugaragara.Bamwe mu barwayi barashobora kwandura indwara zandurira mu myanya y'ubuhumekero kugeza umusonga ukabije, ibibazo by'ubuhumekero bikabije ndetse n'urupfu.

Indwara y'ubuhumekero (RSV) ni virusi ya RNA, ikomoka mu muryango wa paramyxoviridae.Yandura mu bitonyanga byo mu kirere no guhura cyane kandi ni yo ntandaro nyamukuru yandurira mu myanya y'ubuhumekero yo hasi.Impinja zanduye RSV zirashobora kurwara bronchiolitis zikomeye (bita bronchiolitis) na pnewoniya, zifitanye isano na asima mu bana.Impinja zifite ibimenyetso bikomeye, birimo umuriro mwinshi, rhinite, pharyngitis na laryngitis, hanyuma bronchiolitis na pnewoniya.Abana bake barwaye barashobora kugorana nibitangazamakuru bya otitis, pleurisy na myocarditis, nibindi. Indwara zo mu myanya y'ubuhumekero zo hejuru nicyo kimenyetso nyamukuru cyanduza abantu bakuru ndetse nabana bakuru.

Umuyoboro

Izina ry'umuyoboro R6 Buffer Igisubizo A. R6 Igisubizo Buffer B.
FAM SARS-CoV-2 HAdV
VIC / HEX Igenzura ryimbere Igenzura ryimbere
CY5 IFV A. MP
ROX IFV B. RSV

Ibipimo bya tekiniki

Ububiko Amazi: ≤-18 ℃ Mu mwijima;Lyophilized: ≤30 ℃ Mu mwijima
Ubuzima bwa Shelf Amazi: amezi 9;Lyophilized: amezi 12
Ubwoko bw'icyitegererezo Amaraso yose, Plasma, Serumu
Ct ≤38
CV ≤5.0
LoD 300Kopi / mL
Umwihariko Ibisubizo byambukiranya imipaka byerekanaga ko nta reaction yakozwe hagati yigitabo na coronavirus yumuntu SARSr-CoV, MERSr-CoV, HCoV-OC43, HCoV-229E, HCoV-HKU1, HCoV-NL63, virusi ya parainfluenza ubwoko bwa 1, 2, 3, rhinovirus A, B, C, chlamydia pneumoniae, metapneumovirus yumuntu, enterovirus A, B, C, D, virusi y’ibihaha y’abantu, virusi ya epstein-barr, virusi y’iseru, virusi ya cytomegalo, rotavirus, norovirus, virusi ya parotite, virusi ya varicella-zoster, legionella, bordetella pertussis, ibicurane bya haemophilus, staphylococcus aureus, streptococcus pneumoniae, s.pyogène, klebsiella pneumoniae, mycobacterium igituntu, umwotsi aspergillus, candida albicans, candida glabrata, pneumocystis jiroveci hamwe na cryptococcus yavutse hamwe na acide genomic nucleic.
Ibikoresho bikoreshwa Irashobora guhuza ibikoresho nyamukuru bya fluorescent PCR kumasoko

SLAN-96P Sisitemu nyayo-PCR
ABI 7500 Sisitemu nyayo-PCR
ABI 7500 Byihuse-Igihe Cyuzuye PCR
QuantStudio®5 Sisitemu-Igihe nyacyo PCR
UmucyoCycler®480 Sisitemu nyayo-PCR
LineGene 9600 Yongeyeho Sisitemu-Igihe Cyuzuye PCR
MA-6000-Igihe-Cyuzuye Cyumubare Wubushyuhe
BioRad CFX96 Sisitemu nyayo-PCR Sisitemu, BioRad
CFX Opus 96 Sisitemu nyayo-PCR


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