Iki gikoresho kirakoreshwa muri vitro yujuje ubuziranenge bwa polymorphism ya CYP2C9 * 3 (rs1057910, 1075A> C) na VKORC1 (rs9923231, -1639G> A) muri ADN genomic ya ADN yuzuye yamaraso.
Iki gikoresho gikoreshwa muri vitro yujuje ubuziranenge bwa polymorphism ya gen CYP2C19 CYP2C19 * 2 (rs4244285, c.681G> A), CYP2C19 * 3 (rs4986893, c.636G> A), CYP2C19 * 17 (rs12248560, c.806 > T) muri ADN genomic ya ADN yamaraso yose.
Iki gikoresho gikoreshwa mugushakisha ADN yujuje ubuziranenge ubwoko bwa leukocyte antigen yumuntu HLA-B * 2702, HLA-B * 2704 na HLA-B * 2705.
Iki gikoresho gikoreshwa mugushakisha imbuga 2 za mutation ya gen ya MTHFR.Igikoresho gikoresha amaraso yumuntu yose nkicyitegererezo kugirango gitange isuzuma ryiza ryimiterere ya mutation.Irashobora gufasha abaganga gutegura gahunda yo kuvura ikwiranye nuburyo butandukanye butandukanye kurwego rwa molekile, kugirango ubuzima bwabarwayi bugerweho cyane.