Mycobacterium Igituntu Nucleic Acide na Rifampicin Kurwanya

Mycobacterium igituntu ， mugihe gito nka Tubercle bacillus, igituntu, ni bagiteri itera indwara yigituntu.Kugeza ubu, imiti ikoreshwa cyane ku murongo wa mbere wo kurwanya igituntu harimo isoniazid, rifampicin na hexambutol, n'ibindi. Imiti yo ku murongo wa kabiri irwanya igituntu irimo fluoroquinolone, amikacin na kanamycin, n'ibindi. . Icyakora, kubera gukoresha nabi imiti irwanya igituntu hamwe nibiranga imiterere y'urukuta rw'akagari ka mycobacterium igituntu, mycobacterium igituntu itera imiti igabanya imiti igabanya ubukana, izana ibibazo bikomeye mu gukumira no kuvura igituntu.

Rifampicin yakoreshejwe cyane mu kuvura abarwayi b'igituntu cy'ibihaha kuva mu mpera za za 70, kandi igira ingaruka zikomeye.Nibwo buryo bwa mbere bwo kugabanya chimiotherapie y’abarwayi b’igituntu.Kurwanya Rifampicin biterwa ahanini na mutation ya rpoB.Nubwo imiti mishya yo kurwanya igituntu ihora isohoka, kandi n’ubuvuzi bw’abarwayi b’igituntu cy’ibihaha nabwo bwakomeje gutera imbere, haracyari ikibazo cyo kubura imiti igabanya ubukana, kandi ikibazo cyo gukoresha ibiyobyabwenge bidafite ishingiro mu mavuriro ni kinini.Ikigaragara ni uko igituntu cya Mycobacterium ku barwayi bafite igituntu cy'igituntu kidashobora kwicwa mu gihe gikwiye, amaherezo kikaba kiganisha ku ntera zitandukanye zo kurwanya ibiyobyabwenge mu mubiri w'umurwayi, bikongera inzira y'indwara, kandi byongera ibyago byo gupfa k'umurwayi.